Pregnancy: The use of sulfonylurea in pregnancy should generally be avoided because of the risk of neonatal hypoglycemia. Oral hypoglycemic agents are not suitable, insulin is the drug of first choice for treatment of diabetes during pregnancy. It is recommended that oral hypoglycemic therapy is changed to insulin before a pregnancy is attempted, or as soon as pregnancy is discovered.
Lactation: It is not known whether Gliclazide or its metabolites is excreted into breast milk.
The potential for neonatal hypoglycemia in a nursing infant contraindicates use.